Sonic hedgehog signaling in brain development and diseases

Sonic hedgehog (Shh) signaling regulates important biological processes during embryogenesis and adult homeostasis. Deregulation of this essential signaling pathway can lead to congenital defects and tumorigenesis. In this dissertation I explored the functional role of the cholesterol modification o...

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Bibliographic Details
Main Author: Huang, Xi
Other Authors: Vivien A. Casagrande
Format: Others
Language:en
Published: VANDERBILT 2010
Subjects:
Online Access:http://etd.library.vanderbilt.edu//available/etd-03312010-132747/