Sonic hedgehog signaling in brain development and diseases
Sonic hedgehog (Shh) signaling regulates important biological processes during embryogenesis and adult homeostasis. Deregulation of this essential signaling pathway can lead to congenital defects and tumorigenesis. In this dissertation I explored the functional role of the cholesterol modification o...
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Language: | en |
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VANDERBILT
2010
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-03312010-132747/ |