EXPRESSION OF DUB-1 AND DUB-2 AND ANALYSIS OF A ROLE FOR DEUBIQUITINATION IN THE REGULATION OF NUCLEAR FACTOR-KAPPA B
The ubiquitin-proteasome pathway (UPP) is the principal mechanism for the selective degradation of short-lived proteins. The proximal signal for UPP-mediated proteolysis is the covalent modification of target proteins with multiple ubiquitin polypeptides. Protein-ubiquitin conjugation is catalyzed b...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2004
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-04012004-040124/ |