A THEORETICAL APPROACH TO SYNTHETIC VASCULAR GRAFT DESIGN: SURFACE MICRO-TOPOGRAPHY OPTIMIZATION FOR PROMOTING THE RETENTION OF ENDOTHELIAL CELLS
The failure of synthetic vascular grafts due to de-endothelialization of the lumen as a result of exposure to fluid-induced shear stress prevents the widespread use of such grafts as small-diameter vessel replacements. Physical surface modification, an approach that seeks to alter the topography of...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2007
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-04022007-132345/ |