DNA-Protein Cross-Links Induced by Bis-Electrophiles
Diepoxybutane is a mutagenic and carcinogenic oxidation product of the important industrial chemical and environmental contaminant butadiene. The mutagenic potential of diepoxybutane is thought to be due in part to its bifunctional electrophilic character. One mechanism by which bis-electrophiles ca...
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| Language: | en |
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VANDERBILT
2010
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-04102010-225656/ |