REFINING COMPARATIVE PROTEOMICS BY SPECTRAL COUNTING TO ACCOUNT FOR SHARED PEPTIDES AND MULTIPLE SEARCH ENGINES
Spectral counting has become a widely used approach for comparing protein abundance in label-free shotgun proteomics. However, when analyzing complex samples, the ambiguity of matching between peptides and proteins greatly affects the assessment of peptide and protein differentiation. Meanwhile, the...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2012
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-05152012-120718/ |