Regulation of ATR Signaling by CINP and RPA
Genetic instability is a hallmark of cancer. The ATR-ATRIP complex functions at the apex of a cell cycle checkpoint signaling pathway that is critical during every cell division cycle to maintain genome integrity. ATR activity is critical for regulating the firing of replication origins, stabilizing...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2009
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-05272009-174909/ |