Effects of Epilepsy-Associated Mutations on GABAA Receptor Assembly, Trafficking, and Function

GABAA receptors are pentameric, ligand-gated chloride channels that mediate the majority of fast inhibition in the brain. Because they are assembled from an array of 19 subunit subtypes, GABAA receptors are remarkable among neurotransmitter receptors for their potential diversity. Subunit compositi...

Full description

Bibliographic Details
Main Author: Gurba, Katharine Nicole
Other Authors: Alfred George
Format: Others
Language:en
Published: VANDERBILT 2013
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07172013-225446/