Effects of Epilepsy-Associated Mutations on GABAA Receptor Assembly, Trafficking, and Function
GABAA receptors are pentameric, ligand-gated chloride channels that mediate the majority of fast inhibition in the brain. Because they are assembled from an array of 19 subunit subtypes, GABAA receptors are remarkable among neurotransmitter receptors for their potential diversity. Subunit compositi...
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Language: | en |
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VANDERBILT
2013
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-07172013-225446/ |