In silico evaluation of DNA-pooled allelotyping versus individual genotyping for genome-wide association analysis of complex disease.
Recent advances in single nucleotide polymorphism (SNP) genotyping techniques, public databases, and genomic knowledge via the Human Genome Project and the Haplotype Mapping project (HapMap) allow for true genome-wide association (GWA) analysis for common complex diseases such as heart disease, diab...
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Language: | en |
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VANDERBILT
2007
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-07202007-124602/ |