Structural Investigations of N3-(2-Hydroxy-3-buten-1-yl)-2'-deoxyuridine DNA Adducts
Butadiene monoepoxide (BDO) is the major metabolite of butadiene (BD), a widely used petrochemical and known human and animal carcinogen. BD metabolites may be involved in BD-induced carcinogenicity primarily through the production of DNA adducts. Under physiological conditions, BDO alkylates the N3...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2009
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| Online Access: | http://etd.library.vanderbilt.edu//available/etd-07222009-161202/ |