EARLY PANCREAS DEVELOPMENT AND ENDOCRINE INDUCTION: PTF1A AND VEGF
The transcription factor Pdx1 is expressed throughout the pancreas early, but selectively in insulin-producing cells postnatally. Previous studies showed that conserved regulatory regions, Areas I and II (Pdx1PB), directed pancreatic endocrine cell expression, while an adjacent region (Pdx1XB) conta...
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Language: | en |
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VANDERBILT
2007
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-07272007-140331/ |