Hemozoin: a case of heme crystal engineering
During the pathogenic blood stage of a malaria infection, the Plasmodium parasites degrade hemoglobin as a source of nutrition. As a consequence, free heme, known to be toxic to the parasite, is released. It is believed that the parasite circumvents heme toxicity by sequestering the heme molecules i...
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Language: | en |
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VANDERBILT
2010
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-07272010-151453/ |