Regulation of Beta-Cell Mass Expansion by Prostaglandin E2 Signaling
Type 2 diabetes is a major healthcare concern and is characterized by chronic hyperglycemia and low-grade inflammation. Hyperglycemia and systemic inflammation can induce the production of Prostaglandin E2 (PGE2) in islets. PGE2 signals through its four receptors, termed E-Prostanoid (EP) 1-4, to mo...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
VANDERBILT
2017
|
| Subjects: | |
| Online Access: | http://etd.library.vanderbilt.edu/available/etd-08152017-102047/ |