TGF-â IN MAMMARY DEVELOPMENT AND TUMORIGENESIS
The transforming growth factor beta (TGF-â) pathway significantly regulates mammary development and tumorigenesis. In human cancer, its signaling pathways are often modified or lost during tumor progression. Prior to initiation and early during progression TGF-â acts upon the epithelium as a tumor s...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2008
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-08272008-101423/ |