IDENTIFICATION OF THE HEDGEHOG PATHWAY AS A NOVEL THERAPEUTIC TARGET IN MALIGNANT GLIOMAS

Gliomas are the predominant type of primary central nervous system tumors. They are highly invasive and notoriously refractory to current therapies. Patients diagnosed with a malignant glioma face a dismal prognosis that has remained relatively unchanged in the last three decades. A promising novel...

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Bibliographic Details
Main Author: Sarangi, Anuraag
Other Authors: Harold L. Moses
Format: Others
Language:en
Published: VANDERBILT 2009
Subjects:
Online Access:http://etd.library.vanderbilt.edu//available/etd-09282009-041526/