NGN3-EXPRESSING PROGENITOR HETEROGENEITY DRIVES ENDOCRINE LINEAGE ALLOCATION IN PANCREAS DEVELOPMENT
Diabetes is a worldwide health issue. In both type I and late stage type II diabetes, significant beta-cell loss causes insulin deficiency and hyperglycemia. Replenishing beta cells is a promising therapy and it requires enhancing beta-cell replication, activating a beta-cell neogenesis program or t...
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Language: | en |
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VANDERBILT
2015
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-11152015-162440/ |