Structural basis for oligomerization of the eukaryotic replication factor Mcm10

Faithful DNA replication during each cell division cycle is carried out by multiprotein complexes acting at each replication fork. In this complex, DNA unwinding and synthesis activities, driven by the Mcm2-7 helicase and DNA polymerases α, delta and ε, are coordinated by non-enzymatic replication f...

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Bibliographic Details
Main Author: Du, Wenyue
Other Authors: Katherine Friedman
Format: Others
Language:en
Published: VANDERBILT 2013
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11182013-215709/