RADICAL-PROMOTED PEPTIDE CLEAVAGE IN THE GAS-PHASE VIA PEROXYCARBAMATES

Protein identification generally involves enzymatic digestion of proteins followed by mass spectrometry (MS) sequencing analysis of the resulting peptides, a process referred to as bottom-up proteomics. Another approach (top-down proteomics) consists of MS analysis of intact proteins without prior e...

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Bibliographic Details
Main Author: Chacon, Almary
Other Authors: Ned A. Porter
Format: Others
Language:en
Published: VANDERBILT 2007
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11202007-213010/