Mechanistic Insights into Fosfomycin Resistance: Examination of the FosX Class of Fosfomycin Resistance Proteins

The objective of this research was to examine the FosX class of metalloenzymes utilized by pathogenic microorganisms for resistance to the antibiotic fosfomycin. Fosfomycin is an extremely stable natural product produced by strains of soil-dwelling Streptomyces and possesses desirable pharmacologic...

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Bibliographic Details
Main Author: Beihoffer, Lauren Ashley
Other Authors: Richard N. Armstrong
Format: Others
Language:en
Published: VANDERBILT 2005
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11212005-132421/