Immunomodulation of Tumor Associated Macrophages by Targeted, siRNA-Delivering Nanoparticles
Tumor associated macrophages (TAMs) play an important role in establishing a pro-tumor environment in many tumor types. Produce low levels of inflammatory cytokines which creates pro-tumorigenic smoldering inflammation and also TAMs break down the surrounding extracellular matrix, secrete growth fac...
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Format: | Others |
Language: | en |
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VANDERBILT
2014
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-11232014-110428/ |