Differential impact of GAD67 suppression in distinct GABA-ergic interneuron populations: implications for mental illness

GABA-ergic disturbances are hallmark features of many brain disorders. Two transgenic mouse lines were generated to suppress GAD1 in non-overlapping cell types that express cholecystokinin (CCK) or neuropeptide Y (NPY). In situ lipidomic and proteomic analyses on brain tissue sections revealed disti...

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Bibliographic Details
Main Author: Schmidt, Martin Jefferson
Other Authors: Christine Konradi
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-12022013-064125/