MYC AND PIM1 SYNERGISM IN PROSTATE CANCER
The oncogenic PIM1 kinase has been implicated as a cofactor for the oncogene c-MYC in prostate carcinogenesis. In this study, we show that co-expression of c-MYC and PIM1 is associated with high Gleason grade in prostate cancer. Using a tissue recombination model coupled with lentiviral-mediated gen...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2010
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-12042010-030217/ |