Modulation of Synaptic transmission: Quantitative Analysis of Gβγ specificity to adrenergic α2a receptor and SNARE

Modulation of neurotransmitter exocytosis by activated Gi/o coupled G-protein coupled receptors (GPCRs) is a universal regulatory mechanism used both to avoid overstimulation and to influence circuitry. One of the known modulation mechanisms is the Gβγ and soluble N-ethylmaleimide-sensitive factor...

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Bibliographic Details
Main Author: Yim, Yun Young
Other Authors: Kevin L Schey
Format: Others
Language:en
Published: VANDERBILT 2017
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-12042017-135050/