Modeling of interactions between vascular endothelial growth factor family members and their receptors KDR and Flt-1
The vascular endothelial growth factor (VEGF) family is prominently involved in angiogenesis, the formation of new vasculature. Overexpression has been linked to pathological conditions including solid tumor growth. Responses to VEGF are mediated by Flt-1 and KDR, two cell-surface receptors selectiv...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/26569 http://scholar.lib.vt.edu/theses/available/etd-03312008-183133/ |