The effect of spindle geometry on the establishment of merotelic kinetochore attachment and chromosome mis-segregation
At any given time there are on the order of one hundred million cells undergoing mitosis in the human body. To accurately segregate chromosomes, the cell forms the bipolar mitotic spindle, a molecular machine that distributes chromosomes equally to the daughter cells. To this end, microtubules of th...
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Virginia Tech
2014
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Online Access: | http://hdl.handle.net/10919/28241 http://scholar.lib.vt.edu/theses/available/etd-07092012-140818/ |