The effect of spindle geometry on the establishment of merotelic kinetochore attachment and chromosome mis-segregation

At any given time there are on the order of one hundred million cells undergoing mitosis in the human body. To accurately segregate chromosomes, the cell forms the bipolar mitotic spindle, a molecular machine that distributes chromosomes equally to the daughter cells. To this end, microtubules of th...

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Bibliographic Details
Main Author: Silkworth, William Thomas
Other Authors: Biology
Format: Others
Published: Virginia Tech 2014
Subjects:
Online Access:http://hdl.handle.net/10919/28241
http://scholar.lib.vt.edu/theses/available/etd-07092012-140818/