Endogenous Stress Signaling within Human Multicellular Aggregates (Spheroids)
A wide variety of adherent mammalian cells can be induced into a reversible state of metabolic arrest (quiescence) by conversion to non-adherent multicellular aggregates. These "spheroids" can be maintained at room temperature under oxygen- and nutrient-deprived conditions for extended per...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/28407 http://scholar.lib.vt.edu/theses/available/etd-07262006-153655/ |