Polymorphisms in the Flt1 gene and their relation to expression of the secreted Flt1 variant
Vascular endothelial growth factor (VEGF) is a potent angiogenic agent. VEGF activates its biologic responses through two cell-surface receptors, Flt1 and Flk1. In addition to the transmembrane form of Flt1, the Flt1 gene also encodes a secreted, truncated form of the receptor (sFlt1) translated fro...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/29426 http://scholar.lib.vt.edu/theses/available/etd-11012009-210522/ |