Targeting brain inflammation with bioconjugated nanoparticles

Brain inflammation has been implicated with the pathogenesis of neurodegenerative diseases. Activated microglia and endothelial cells induce production of reactive oxygen species (ROS) and overexpress pro-inflammatory mediators that perpetuate tissue damage. Current treatments are not effective agai...

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Bibliographic Details
Main Author: Hirani, Anjali
Other Authors: Biomedical Engineering
Format: Others
Published: Virginia Tech 2014
Subjects:
Online Access:http://hdl.handle.net/10919/33655
http://scholar.lib.vt.edu/theses/available/etd-06192009-214318/