Cd44-Hyaluronic Acid Interactions in Il-2 Induced Vascular Leak Syndrome
Immunotherapy with IL-2 is accompanied by severe toxicity leading to development of vascular leak syndrome (VLS). Previous studies from our laboratory demonstrated that CD44 knockout mice exhibit marked decrease in IL-2 induced VLS, thereby suggesting a role for CD44 in VLS. In the current study we...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/33821 http://scholar.lib.vt.edu/theses/available/etd-06302001-001618/ |