Local Administration of Botulinum Toxin Type-B in the External Anal Sphincter of Horses Produces Transient Reduction of Peak Anal Pressure
Toxins produced by the Gram-positive bacteria Clostridium botulinum cause transient chemodenervation of mammalian muscle. The toxin binds to specific proteins within cholinergic presynaptic nerve terminals which regulate the release of acetylcholine in the synaptic space resulting is loss of muscle...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/33927 http://scholar.lib.vt.edu/theses/available/etd-07082003-131743/ |