Quantitative Analysis of a Cell Cycle Checkpoint in Xenopus laevis Cell-Free Egg Extracts
In somatic cells, checkpoint pathways trigger cell cycle arrest in response to unreplicated or damaged DNA by inhibiting the activity of cyclin-dependent kinases (Cdks). In the Xenopus laevis embryo, checkpoints are not operational until the midblastula transition (MBT). Studies in cell-free egg ext...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/34734 http://scholar.lib.vt.edu/theses/available/etd-08242005-123051/ |