Effect of homozygous lpr and gld mutations on the immune functions and induction of autoimmunity
The murine <i>lpr</i> gene encodes for an aberrant form of Fas (CD95), a molecule involved in apoptosis. The mouse <i>gld</i> gene leads to the expression of a defective Fasligand. Mice homozygous for <i>lpr</i> or <i>gld</i> mutations develop severe l...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/38209 http://scholar.lib.vt.edu/theses/available/etd-06062008-162732/ |