Immunotoxicity of TCDD: role of Fas expression and MHC phenotype on TCDD-mediated thymic artophy and decrease in peripheral T cell responsiveness

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is well known for its immunotoxic effects particularly on the thymus as well as on T and B lymphocyte functions. Previous studies have suggested that TCDD may induce apoptosis in thymocytes although its demonstration in vivo has met with limited success. TC...

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Bibliographic Details
Main Author: Rhile, Mark Joseph
Other Authors: Biology
Format: Others
Language:en
Published: Virginia Tech 2014
Subjects:
Online Access:http://hdl.handle.net/10919/40826
http://scholar.lib.vt.edu/theses/available/etd-01312009-063044/