Identification of native co-factors of MshB and MCA from Mycobacterium species

Mycothiol (MSH), a low-molecular- weight thiol, is a primary reducing agent and essential for the survival of mycobacteria. The full pathway of MSH biosynthesis and detoxification includes various promising drug targets. Several metalloenzymes are involved in this pathway, such as a deacetylase (Msh...

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Bibliographic Details
Main Author: Kocabas, Evren
Other Authors: Biochemistry
Format: Others
Published: Virginia Tech 2014
Subjects:
MCA
Online Access:http://hdl.handle.net/10919/44457
http://scholar.lib.vt.edu/theses/available/etd-08262010-130942/