Identification of native co-factors of MshB and MCA from Mycobacterium species
Mycothiol (MSH), a low-molecular- weight thiol, is a primary reducing agent and essential for the survival of mycobacteria. The full pathway of MSH biosynthesis and detoxification includes various promising drug targets. Several metalloenzymes are involved in this pathway, such as a deacetylase (Msh...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/44457 http://scholar.lib.vt.edu/theses/available/etd-08262010-130942/ |