Comparison of two saline loading protocols for preventing nephrotoxicosis associated with high-dose cisplatin
<p>Cisplatin is an antineoplastic drug used to treat malignant tumors in human beings and dogs. Nephrotoxicosis was initially considered dose limiting. The use of saline loading and hypertonic saline administration protocols allowed dose escalation, reduced nephrotoxicosis, and increased remis...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/44604 http://scholar.lib.vt.edu/theses/available/etd-09052009-040811/ |