Stereochemical aspects of virginiamycin biosynthesis: biosynthesis of antibiotic A33853
The biochemical pathways for the formation of the unusual amino acids found in virginiamycin M₁ and A33853 were investigated. Specifically tritiated and carbon 14 labeled serines were incorporated into virginiamycin M₁. (2S)-serine and (2S,3R)-[3-³H] serine were found to be precursors, thus giving e...
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Format: | Others |
Language: | en_US |
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Virginia Polytechnic Institute and State University
2015
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Online Access: | http://hdl.handle.net/10919/54266 |