Vinylcyclopropanation of enones in [2+3] cyclopentene annulation: application to the total synthesis of (-)-retigeranic acid
The addition of the Iithium dienolate 161a derived from ethyl 2-bromocrotonate (163) to several enones provided vinylcyclopropanes of type 165 which were converted by thermolysis to the corresponding cyclopentenes in an overall [2+3] annulation process. [see document for diagram of chemical compoun...
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| Format: | Others |
| Language: | en_US |
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Virginia Polytechnic Institute and State University
2015
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| Online Access: | http://hdl.handle.net/10919/54267 |