Enantioselective Synthesis of Drug-like Molecules via Axially-Chiral Intermediates
The self-regeneration of stereocenters via stereolabile axially-chiral intermediates (SRSvSACI) is a synthetic strategy in which the configuration of a starting material, possessing only a single stereocenter, directs the formation of a chiral axis in an intermediate. The reaction proceeds stereospe...
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| Format: | Others |
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Virginia Tech
2016
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| Online Access: | http://hdl.handle.net/10919/71675 |