Genomic Instability and Gene Dosage Obscures Clues to Virulence Mechanisms of F. tularensis species

Genomic Instability and Gene Dosage Obscures Clues to Virulence Mechanisms of F. tularensis species

The pathogen Francisella tularensis subsp. tularensis has been classified as a Center for Disease Control (CDC) select agent. However, little is still known of what makes the bacteria cause dis-ease, especially the highly virulent type A1 strains. The work in this dissertation focused on type A1 str...

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Bibliographic Details
Main Author: Modise, Thero
Other Authors: Animal and Poultry Sciences
Format: Others
Published: Virginia Tech 2016
Subjects:
Francisella tularensis
genome instability
vaccine
transposase
inversion
duplica-tion
deletion
RNAseq
DNAseq
Assembly
Gene Dosage
Pathogen
Online Access:http://hdl.handle.net/10919/72885

Internet

http://hdl.handle.net/10919/72885

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