Chemical modification of catalytically essential functional groups in the active site of papain
A new technique for conversion of carboxylic acids to carbinols under mild conditions has been developed. This technique requires first formation of enol esters by coupling N-ethyl-5-phenylisoxazolium3' -sulfonate with an appropriate carboxylic acid in acetonitrile, followed by reduction with a...
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| Format: | Others |
| Language: | en_US |
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Virginia Polytechnic Institute and State University
2019
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| Online Access: | http://hdl.handle.net/10919/87303 |