Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis

The liver is responsible for lipid and glucose metabolism, protein and bile synthesis and the biotransformation of xenobiotics. These functions, performed by hepatocytes, are dependent on heterotypic interactions with other liver cell types and the stratified microarchitecture of the organ. In vitro...

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Bibliographic Details
Main Author: Orbach, Sophia Michelle
Other Authors: Chemical Engineering
Format: Others
Published: Virginia Tech 2019
Subjects:
Online Access:http://hdl.handle.net/10919/93313