Effects of Cysteine Modification on Microtubule-Motor Protein Function and Tubulin Assembly
Chemical modification is a powerful technique for probing functionally important amino acids. N-ethylmaleimide (NEM) reacts readily with exposed sulfhydryl groups, and has previously been shown to inhibit the activity of MT-motor proteins and tubulin assembly. This project seeks to investigate the m...
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Virginia Tech
2011
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| Online Access: | http://hdl.handle.net/10919/9876 http://scholar.lib.vt.edu/theses/available/etd-012899-114123 |