Synthesis of Inhibitors of Steroid Sulfatase and Towards the Synthesis of a Chiral Electrophilic Fluorinating Reagent

Steroid sulfatase (STS) catalyzes the desulfation of sulfated steroids such as estrone sulfate to the corresponding steroid such as estrone. Inhibitors of STS are believed to have potential for treating estrogen-dependent breast cancer. A new class of potential irreversible suicide inhibitors of ST...

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Bibliographic Details
Main Author: Liu, Yong
Format: Others
Language:en
Published: 2007
Subjects:
Online Access:http://hdl.handle.net/10012/2722