Peptide Mediated siRNA Delivery: Physicochemical and in vitro Characterizations
Short interfering RNAs (siRNAs) trigger RNA interference (RNAi) both in vitro and in vivo, where the expression of the encoded protein is silenced. Its potential use as a therapeutic agent is limited by its rapid enzymatic degradation and low cellular uptake. Therefore, a delivery carrier is desired...
| Main Author: | |
|---|---|
| Language: | en |
| Published: |
2008
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10012/3504 |