Dynamics and Inhibition of Class II Fructose 1,6-bisphosphate Aldolase
It has been suggested for many decades that the essential and ubiquitous enzyme fructose 1,6-bisphosphate aldolase (FBA) could be a good drug target against bacteria and fungi, since lower organisms possess a metal-dependent (Class II) FBA, as opposed to higher organisms which possess a Schiff-base...
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| Language: | en |
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2009
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| Online Access: | http://hdl.handle.net/10012/4325 |