Tracing the molecular and evolutionary determinants of novel functions in protein families
This thesis explores the limits of homology-based inference of protein function and evolution, where overall similarity between sequences can be a poor indicator of functional similarity or evolutionary relationships. Each case presented has undergone different patterns of evolutionary change due to...
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| Language: | en |
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2010
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| Online Access: | http://hdl.handle.net/10012/5052 |