Fluorescence studies on anthrax protective antigen pore formation and in the presence of the host receptor, CMG2

The anthrax toxin secreted by Bacillus anthracis is the major virulence factor of anthrax disease. The protective antigen (PA) component of the toxin binds to the von-Willebrand factor A (vWA) domain of capillary morphogenesis protein 2 (CMG2), followed by proteolytic cleavage into two fragments of...

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Bibliographic Details
Main Author: Andra, Kiran K.
Other Authors: Bann, James G.
Format: Others
Language:en_US
Published: Wichita State University 2013
Subjects:
Online Access:http://hdl.handle.net/10057/6385