Fluorescence studies on anthrax protective antigen pore formation and in the presence of the host receptor, CMG2
The anthrax toxin secreted by Bacillus anthracis is the major virulence factor of anthrax disease. The protective antigen (PA) component of the toxin binds to the von-Willebrand factor A (vWA) domain of capillary morphogenesis protein 2 (CMG2), followed by proteolytic cleavage into two fragments of...
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Format: | Others |
Language: | en_US |
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Wichita State University
2013
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Online Access: | http://hdl.handle.net/10057/6385 |