A Study on the Protein Interaction with Different Platinum Compounds

Since the discovery of anti-tumor activity of cisplatin in 1960, significant progress has been made in treating metastatic or advanced cancer with cisplatin and platinum compounds. Platinum compounds covalently bind to DNA and disrupt DNA function. They are also known to bind with amino acids like m...

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Bibliographic Details
Main Author: Kotadia, Nayna
Format: Others
Published: TopSCHOLAR® 2008
Subjects:
Online Access:http://digitalcommons.wku.edu/theses/8
http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1007&context=theses