Reinventing Aromatic Substitution: A Novel Look
Electrophilic aromatic substitution (EAS) and directed ortho-metalation (DoM) involve the direct substitution of an arene hydrogen. A major drawback involving EAS is the necessity for harsh forcing conditions for the reaction to proceed. Catalysts such as Lewis acids FeBr3 and AICI3 for the introduc...
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TopSCHOLAR®
2013
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Online Access: | http://digitalcommons.wku.edu/theses/1292 http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=2295&context=theses |