Functionalization and Modification of Naphthaquinone Analogs as HER2 Kinase Inhibitors
HER2 overexpression in breast cancer tumors predicts lower overall survival. Because of the aggressive nature of HER2 tumors and the association with metastatic disease, the HER2 receptor holds great promise as a therapeutic target in metastatic breast cancer. We are developing small molecule inhibi...
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| Format: | Others |
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TopSCHOLAR®
2014
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| Online Access: | http://digitalcommons.wku.edu/theses/1325 http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=2328&context=theses |