The Effects of Carrier Ligands on Cisplatin Binding to Cysteine and Methionine
We have reacted several derivatives of the anticancer drug cisplatin with N-acetyl-Lcysteine (N-AcCys) and N-acetyl-L-methionine (N-AcMet), which are two of the primary amino acid targets of platinum. NMR spectroscopy was used to monitor the reactions and determine the effect the different ligands w...
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| Format: | Others |
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TopSCHOLAR®
2017
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| Online Access: | http://digitalcommons.wku.edu/theses/1969 http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=2972&context=theses |